Thermo Fisher Scientific SARS-CoV-2 Nucleocapsid Monoclonal Antibody (HL455)
SARS-CoV-2 및 SARS-CoV 핵단백질을 인식하는 토끼 단클론 항체. Western blot, IHC, ICC/IF, ELISA에 사용 가능. 높은 특이성과 재현성을 제공하며, MERS-CoV와 교차 반응 없음. 연구용으로 COVID-19 관련 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL455 |
| Immunogen | Full length SARS-CoV-2 (COVID-19) nucleocapsid recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890569 |
Product Specific Information
This antibody detects both SARS-CoV nucleocapsid and SARS-CoV-2 nucleocapsid proteins. Internal testing indicates no cross-reactivity with MERS-CoV nucleocapsid protein.
Target Information
SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid and is the most abundant protein in coronavirus. Due to its strong immunogenicity, it has potential diagnostic value for SARS-CoV-2. The N protein is an RNA-binding protein essential for viral genome packaging and contains three dynamic disordered regions with transiently-helical binding motifs. Its two folded domains interact minimally, making it a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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