Thermo Fisher Scientific SPIN2 Polyclonal Antibody
Thermo Fisher Scientific SPIN2 polyclonal antibody는 인간 및 생쥐 SPIN2 단백질을 검출하는 고품질 항체입니다. Western blot과 IHC(P)에서 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- PA550266
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SPIN2 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of Human SPIN2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635719 |
Product Specific Information
This antibody detects endogenous levels of total SPIN2 protein.
Target Information
Human SPIN2 expressed by two IL3-dependent murine myeloid cell lines showed moderate antiapoptotic activity after IL3 removal but was unable to prevent apoptosis induced by doxorubicin. SPIN2-expressing cells were more sensitive to doxorubicin-mediated cell death. Additionally, SPIN2 did not counteract Fas ligand-induced apoptosis in Jurkat human T-cell lines. Deletion of the C-terminal amino acids reduced its antiapoptotic activity. In murine myeloid cells, SPIN2 overexpression increased doubling time and slowed growth rate, with an elevated percentage of cells in G2/M phase, especially after IL3 withdrawal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-50266_SPIN2_Q9BPZ2-1_Rabbit.svg, PA5-50266_SPIN2_Q9BPZ2-1_Rabbit_PDP.jpeg)
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