Thermo Fisher Scientific LEF1 Polyclonal Antibody
LEF1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 LEF1 합성 펩타이드로부터 유래했으며, 다양한 종에 교차 반응성을 보입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA124462
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 0.2–2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human LEF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2234573 |
Product Specific Information
- Recommended positive controls: Human fetal heart, Transfected 293T
- Predicted reactivity:
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 86%; Mouse: 79%; Pig: 93%; Rabbit: 93%; Rat: 79% - Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway and may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors and have also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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