Thermo Fisher Scientific SMAD6 Polyclonal Antibody
SMAD6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 다양한 종에서 높은 예측 반응성 보유. 연구용으로 TGF-β 및 BMP 신호 억제 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide region of human MADH6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_559985 |
Product Specific Information
- Recommended positive controls: Jurkat
- Predicted reactivity: Cow (100%), Dog (100%), Guinea Pig (93%), Horse (91%), Mouse (100%), Pig (100%), Rat (100%), Zebrafish (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta type 1 receptor superfamily members.
It selectively inhibits BMP (bone morphogenetic protein) signaling by competing with co-SMAD SMAD4 for receptor-activated SMAD1.
SMAD6 is classified as an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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