
Thermo Fisher Scientific TLR8 Monoclonal Antibody (44C143)
TLR8 단백질을 인식하는 마우스 단클론 항체로, 인간 및 마우스 시료에 반응합니다. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 사용 가능합니다. KLH-결합 합성 펩타이드 면역원으로 제작되었으며, Protein G로 정제된 액상 형태입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | – |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | – |
| Flow Cytometry (Flow) | 0.5–1 µg per million cells | 1 publication |
| Dot Blot (DB) | Assay-Dependent | – |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Human, Mouse, Rabbit |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 44C143 |
| Immunogen | KLH-conjugated synthetic peptide of human TLR8, within amino acids 750–850. Cross-reacts with mouse TLR8. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2537709 |
Additional Formats
Target Information
The TLR8 protein is a member of the Toll-like receptor (TLR) family, which plays a key role in pathogen recognition and activation of innate immunity. TLRs are conserved from Drosophila to humans and recognize pathogen-associated molecular patterns (PAMPs) on infectious agents, mediating cytokine production for effective immune response.
TLR8 is predominantly expressed in lung and peripheral blood leukocytes and is located near TLR7 on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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