Thermo Fisher Scientific LYK5 Polyclonal Antibody
LYK5 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA, IP 등에 사용 가능. Human 및 비인간 영장류 반응성. 합성 펩타이드(AA 50-100)로 면역화. 친화 크로마토그래피로 정제된 액상 형태로, 0.5–1.5 mg/mL 농도. 연구용 한정.
- 카탈로그번호
- STRAD-101AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 50–100 on human STE-20 related kinase adapter protein alpha (LYK5, UniProt ID: Q7RTN6-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | Proprietary buffer, pH 7.4–7.8, containing 0.5% BSA and 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
LYK5 (STE20-related Adaptor Protein, STRAD; FLJ90524)
Gene locus: 17q23.3
Members of the STE-20-like kinase family stimulate MAPK pathways by directly activating MAPKKK. STRAD is a pseudokinase member of this family, containing a STE-20-like kinase domain but lacking residues required for catalytic activity. It specifically binds LKB1 and regulates its tumor suppressor functions by acting as an upstream activator and directing its subcellular localization. STRAD-LKB1 interaction leads to phosphorylation of STRAD and enhances LKB1 autophosphorylation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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