Thermo Fisher Scientific HVCN1 Polyclonal Antibody
Thermo Fisher Scientific의 HVCN1 Polyclonal Antibody는 인간 HVCN1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 IHC에 사용됩니다. 동결건조 형태로 제공되며, 연구용으로만 사용 가능합니다. 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 2–100 of human HVCN1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: HVCN1.
Target Information
HVCN1 (hydrogen voltage-gated channel 1) is a voltage-gated proton channel protein highly expressed in immune tissues. It mediates proton conductance required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates voltage-dependent proton permeability of excitable membranes by allowing proton flow according to their electrochemical gradient. It is sensitive to zinc ions and can be inhibited by them. HVCN1 may represent a potential therapeutic target for B cell malignancies involving continued signaling via the B cell antigen receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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