Thermo Fisher Scientific FGFR2 Monoclonal Antibody (OTI5C5), TrueMAB
FGFR2 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, ICC/IF, Flow cytometry에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 동결건조 형태로 안정적 보관 가능. 연구용으로 세포신호 및 질병 관련 연구에 활용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C5 |
| Immunogen | Full-length human recombinant FGFR2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
FGFR2 is a receptor tyrosine kinase belonging to the FGFR family, which regulates cellular functions such as angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, differentiation, and tissue repair.
Mutations in FGFR2 are associated with various syndromes including Crouzon, Pfeiffer, Apert, Jackson-Weiss, Beare-Stevenson, Saethre-Chotzen, and syndromic craniosynostosis.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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