Thermo Fisher Scientific Phospho-JNK1/2/3 (Thr183, Tyr185) Polyclonal Antibody
Phospho-JNK1/2/3 (Thr183, Tyr185) 항체로 다양한 종에서 반응하며, Western blot, IHC, ICC, Flow Cytometry, ELISA 등에 사용 가능. Rabbit polyclonal IgG로 제조되었으며, Protein A로 정제됨. 세포 신호전달 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Mouse, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS (pH 7.4), 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. These kinases are serine-threonine protein kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus. JNK is involved in diverse cellular processes such as proliferation, differentiation, transcription regulation, and development. JNK pathways are activated by stress and inflammatory signals, and the protein exists as ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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