Thermo Fisher Scientific UNC45A Polyclonal Antibody
UNC45A 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ICC/IF에 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피 정제, 액상 형태. 세포 내 단백질 접힘 및 근육세포 발달 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UNC45A. Recombinant protein control fragment (Product #RP-98108) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649269 |
Product Specific Information
Immunogen sequence:
QELQHRGAVV VLNMVEASRE IASTLMESEM MEILSVLAKG DHSPVTRAAA ACLDKAVEYG LIQPNQDG
Highest antigen sequence identity to the following orthologs:
- Mouse: 82%
- Rat: 84%
Target Information
UNC45A, also named as SMAP1, acts as a co-chaperone for HSP90. UNC45A prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. It promotes PGR function in the cell and is essential for proper folding of myosin, normal cell proliferation, myotube formation, and myosin accumulation during muscle cell development. Additionally, UNC45A plays a role in erythropoiesis in stroma cells of the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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