Thermo Fisher Scientific UNC45A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human UNC45A. Recombinant protein control fragment (Product #RP-98108). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UNC45A,uniProtId:Q9H3U1-1,ncbiNodeId:9606,antigenRange:876-943,antigenLength:944,antigenImageFileName:PA5-58703_UNC45A_Q9H3U1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58703_UNC45A_Q9H3U1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649269

Product Specific Information

Immunogen sequence: QELQHRGAVV VLNMVEASRE IASTLMESEM MEILSVLAKG DHSPVTRAAA ACLDKAVEYG LIQPNQDG

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.

Target Information

UNC45A, also named as SMAP1, acts as co-chaperone for HSP90. UNC45A prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. It is a positive factor in promoting PGR function in the cell. It is necessary for proper folding of myosin and necessary for normal cell proliferation, normal myotube formation and myosin accumulation during muscle cell development. UNC45A plays a role in erythropoiesis in stroma cells in the spleen.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.