Thermo Fisher Scientific QPRT Monoclonal Antibody (OTI4B3), TrueMAB
인간 QPRT 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 유세포분석에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 저장. 신경퇴행성 질환 연구용으로 적합한 연구 전용 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B3 |
| Immunogen | Full length human recombinant protein of human QPRT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.39 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
QPRT gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan–nicotinamide adenine dinucleotide pathway. Quinolinate acts as a potent endogenous excitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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