Thermo Fisher Scientific MEF2B Polyclonal Antibody
Rabbit polyclonal antibody against MEF2B for WB and IHC applications. Reacts with human, mouse, and rat. Affinity purified with >95% purity. Supplied as liquid, 1 mg/mL in PBS with 0.05% sodium azide. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 80–120 of Human MEF2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4 °C short term; for long-term storage, store at −20 °C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718968 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The myocyte enhancer factor-2 (MEF-2) family of transcription factors associates with co-repressors or co-activators to regulate the development and function of T cells, neuronal cells, and muscle cells. Four family members arise from alternatively spliced transcripts (MEF-2A, -2B, -2C, and -2D). These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation of the four transcripts implies functional distinction during embryogenesis and development. Differentiation from mesodermal precursor cells to myoblasts has revealed tissue-specific factors that regulate muscle gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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