Thermo Fisher Scientific CD267 (TACI) Polyclonal Antibody
Human CD267 (TACI)에 특이적인 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보존. 면역 반응 및 B세포 관련 연구용으로 적합.
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Thermo Fisher Scientific CD267 (TACI) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human CD267 (TACI). Recombinant protein control fragment (Product #RP-102143). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856409 |
Product Specific Information
Immunogen sequence:
ACFLKKRGDP CSCQPRSRPR QSPAKSSQDH AMEAGSPVST SPEPVETCSF CFPECRAPTQ ESAVTPGTPD PTCAGRWGCH TRTTVLQPCP HIPDSGLGIV CVPAQE
Target Information
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively.
BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth.
Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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