Thermo Fisher Scientific Cytokeratin 1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 200-450 of human Cytokeratin 1 (Cytokeratin 1 (KRT1)) (NP_0061123) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 1,uniProtId:P04264-1,ncbiNodeId:9606,antigenRange:200-450,antigenLength:644,antigenImageFileName:PA5-88276_Cytokeratin_1_P04264-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88276_Cytokeratin_1_P04264-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804793

Product Specific Information

Immunogen sequence: FLEQQNQVLQ TKWELLQQVD TSTRTHNLEP YFESFINNLR RRVDQLKSDQ SRLDSELKNM QDMVEDYRNK YEDEINKRTN AENEFVTIKK DVDGAYMTKV DLQAKLDNLQ QEIDFLTALY QAELSQMQTQ ISETNVILSM DNNRSLDLDS IIAEVKAQYE DIAQKSKAEA ESLYQSKYEE LQITAGRHGD SVRNSKIEIS ELNRVIQRLR SEIDNVKKQI SNLQQSISDA EQRGENALKD AKNKLNDLED A; Positive Samples: Mouse brain, Rat brain; Cellular Location: Cell membrane

Target Information

Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.