Thermo Fisher Scientific CCDC94 Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(Paraffin)에서 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. CCDC94 단백질 검출 및 스플라이소솜 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CCDC94. Recombinant protein control fragment (Product # RP-98975) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639505 |
Product Specific Information
Immunogen sequence:
ITFKTDPENT DYTMEHGATR NFQAEKLLEE EEKRVQKERE DEELNNPMKV LENRTKDSKL EMEVLENLQE LK
Antigen sequence identity:
- Mouse: 100%
- Rat: 99%
Target Information
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961).
Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.
May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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