Thermo Fisher Scientific MRPL42 Monoclonal Antibody (3H6G11)
Thermo Fisher Scientific MRPL42 단클론 항체(3H6G11)는 인간 MRPL42 단백질을 검출하기 위한 고특이성 항체입니다. Western blot, IHC, ICC/IF, Flow cytometry 및 ELISA에 적합합니다. 단클론 Mouse IgG1 형식으로, Protein G로 정제되어 높은 순도와 안정성을 제공합니다.
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Thermo Fisher Scientific MRPL42 Monoclonal Antibody (3H6G11)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:300 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3H6G11 |
| Immunogen | Purified recombinant fragment of human MRPL42 (amino acids 142–203) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538599 |
Product Specific Information
MA5-17128 targets MRPL42 in indirect ELISA, FACS, ICC, IHC, IF, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human MRPL42 (amino acids 142–203) expressed in E. coli.
MA5-17128 detects MRPL42, which has a predicted molecular weight of approximately 16.7 kDa.
Target Information
MRPL42 is part of the mammalian mitochondrial ribosomal protein family, encoded by nuclear genes and involved in mitochondrial protein synthesis. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with an estimated 75% protein to rRNA composition, opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA.
The MRPL42 gene encodes a protein identified in both 28S and 39S subunits. Alternative splicing results in multiple transcript variants, and pseudogenes are found on chromosomes 4q, 6p, 6q, 7p, and 15q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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