Thermo Fisher Scientific IFN beta Recombinant Rabbit Monoclonal Antibody (1O1F5)
마우스 IFN-beta를 인식하는 재조합 토끼 단클론 항체. Western blot 및 ELISA에 최적화. HEK293 세포에서 발현된 IgG 형식의 항체로, Protein A로 정제됨. -20°C에서 보관하며 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:7,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1O1F5 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–182 of mouse IFN-beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
MNNRWILHAA FLLCFSTTAL SINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN
Target Information
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit tumor development. IFN-beta binding activates the tyrosine kinases Jak1 and Tyk2, leading to phosphorylation of STAT transcription factors and induction of immune response genes. Toll-like receptor (TLR) family members can also stimulate IFN-beta production. IFN-beta is used clinically for treating tumors, infections, and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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