Thermo Fisher Scientific DAB1 Polyclonal Antibody
Thermo Fisher Scientific의 DAB1 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제된 비결합형 항체로, 신경 발달 연구에 적합합니다. PBS 버퍼와 글리세롤 포함, 안정적 보관 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DAB1. Recombinant protein control fragment (Product #RP-103113). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640363 |
Product Specific Information
Immunogen sequence:
TPAPRQSSPS KSSASHASDP TTDDIFEEGF ESPSKSEEQE APDGSQASSN SDPFGEPSGE PSGDNISPQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 96%
Target Information
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer.
This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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