Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody
TRAF3IP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin)에서 검증됨. 인간 및 마우스 반응성, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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- PA550277
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human TNF receptor-associated factor 3 interacting protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635730 |
Product Specific Information
This antibody detects endogenous levels of total TRAF3IP1 protein.
Target Information
Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation, and apoptosis in various cell types. TNFR-associated factors (TRAFs) are proteins that act as downstream signal transducers for the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region essential for signaling. MIP-T3 associates with TRAF3, binds taxol-stabilized microtubules and tubulin, and recruits TRAF3 to microtubules when overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3, suggesting a mechanism for sequestering TRAF3 to the cytoskeletal network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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