Thermo Fisher Scientific KLHL29 Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).

Target Information

KLHL29 (Kelch-like protein 29), also known as KBTBD9, is a 655 amino acid protein related to the Drosophila Kelch protein. Mutations affecting Kelch function result in failure of Kelch to associate with ring canals, leading to female sterility.
Human KLHL29 contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers.
Proteins containing BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function.
KLHL29 exists as two alternatively spliced isoforms, encoded by a gene that maps to human chromosome 2p24.1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.