Thermo Fisher Scientific NAPSA Monoclonal Antibody (OTI3E5), TrueMAB
인간 NAPSA 단백질(아미노산 64-244)에 특이적인 마우스 단클론 항체. IHC 및 ICC/IF 실험에 사용 가능. 동결건조 형태로 제공되며, PBS와 trehalose 버퍼에 보관. 암 연구 및 종양 감별용 바이오마커 연구에 적합.
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Thermo Fisher Scientific NAPSA Monoclonal Antibody (OTI3E5), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 64–244 of human NAPSA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882.
Target Information
Napsin 1 is an aspartic protease primarily expressed in the lung, and also found in kidney and metastatic carcinomas.
It processes surfactant protein B in pulmonary and renal tissues, but its regulation changes during carcinogenesis.
Napsin evaluation aids in identifying various cancers and differentiating primary tumors from metastases.
When combined with thyroid transcription factor analysis, Napsin serves as a specific biomarker for carcinoma differentiation.
It is also associated with pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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