Thermo Fisher Scientific CACNA1F Polyclonal Antibody
Rabbit polyclonal antibody targeting human CACNA1F, suitable for IHC and ELISA. Recognizes voltage-sensitive calcium channel alpha-1F isoform. Provided in liquid form, 1 mg/mL concentration, Protein A purified. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:300
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CACNA1F, amino acids 1001–1100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are involved in calcium-dependent processes such as muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death.
The isoform alpha-1F gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the high-voltage activated (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and omega-agatoxin-IIIA (omega-Aga-IIIA), but are insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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