Thermo Fisher Scientific APOE Monoclonal Antibody (OTI2A4), TrueMAB
APOE 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western Blot 및 IHC(P) 분석에 적합. 고순도 친화 크로마토그래피 정제 제품으로, 라이오필라이즈 형태 제공. 인간 APOE 전체 길이 재조합 단백질을 면역원으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A4 |
| Immunogen | Full length human recombinant protein of human APOE produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Apolipoprotein E (Apo E) is involved in plasma lipid metabolism and is a component of various plasma lipoprotein-lipid particles. It is synthesized in the liver, brain, spleen, and kidney, with high concentrations in interstitial fluids. Apo E facilitates the redistribution of cholesterol between cells and contributes to the formation of very low-density lipoproteins and chylomicrons.
The Apo E gene is located on chromosome 19 at position 19q13.2.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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