Thermo Fisher Scientific TNFR2 (soluble) Polyclonal Antibody
인간 TNFR2 단백질을 인식하는 Goat Polyclonal 항체. Western blot 및 Immunocytochemistry에 사용 가능. 비결합형 액상 형태로 제공되며, PBS 버퍼에 5% 트레할로스 함유. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human sTNF RII expressed in E. coli. This recombinant protein represents the non-glycosylated, N-terminal methionyl form of the naturally occurring human soluble type II receptor for TNF, minus 53 amino acids from the proline-rich region just exterior to the transmembrane domain. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | IgG fraction |
| Storage buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1958754 |
Product Specific Information
- Recommended positive controls: human peripheral blood lymphocytes
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha.
The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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