Thermo Fisher Scientific DOK7 Monoclonal Antibody (OTI5G8), TrueMAB
DOK7 단백질을 표적으로 하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, Flow cytometry에 사용 가능. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보관. 신경근 시냅스 형성 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G8 |
| Immunogen | Full length human recombinant DOK7 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by DOK7 is essential for neuromuscular synaptogenesis. It functions in aneural activation of muscle-specific receptor kinase, required for postsynaptic differentiation and clustering of the acetylcholine receptor in myotubes. Mutations in this gene are associated with familial limb-girdle myasthenia autosomal recessive (congenital myasthenic syndrome type 1B). Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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