Thermo Fisher Scientific HOXA5 Monoclonal Antibody (4E2)
HOXA5 단백질을 인식하는 Mouse IgM 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용되며, p53 관련 종양 억제 연구에 활용 가능합니다.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E2 |
| Immunogen | HOXA5 (NP_061975, 약 91–200 a.a) 부분 재조합 단백질, GST 태그 포함 (GST 태그 MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
TSTHSPQPDP LPCSAVAPSP GSDSHHGGKN SLSNSSGASA DAGSTHISSR EGVGTASGAE EDAPASSEQA SAQSEPSPAP PAQPQIYPWM RKLHISHDNI GGPEGKRART
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.
HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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