Thermo Fisher Scientific CNTF Monoclonal Antibody (AS23)
인간 CNTF 단백질을 검출하는 마우스 단클론 항체로, Western blot, ELISA, Immunoprecipitation에 사용 가능. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도. 신경세포 생존 및 신경전달 관련 연구에 적합.
- 카탈로그번호
- MA125948
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–5 µg/mL | |
| ELISA | 10 µg/mL | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AS23 |
| Immunogen | This information is considered to be commercially sensitive. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_779859 |
Product Specific Information
MA1-25948 detects CNTF from human samples.
Target Information
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system, where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein acts as a potent survival factor for neurons and oligodendrocytes and may reduce tissue destruction during inflammatory attacks.
A mutation in this gene resulting in aberrant splicing leads to ciliary neurotrophic factor deficiency, though this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequences has been identified but is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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