Thermo Fisher Scientific MCP-1 Monoclonal Antibody (S14)
인간 MCP-1(CCL2)을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ELISA, 중화 및 억제 실험에 적합합니다. 단백질 G로 정제된 액상형 제품이며, 보존제 무첨가 PBS(pH 7.2) 용액에 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- MA126057
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MCP-1 Monoclonal Antibody (S14)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1.0 µg/mL |
| ELISA (ELISA) | Assay-dependent |
| Neutralization (Neu) | 0.5 µg/mL |
| Inhibition Assays (IA) | 0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S14 |
| Immunogen | Recombinant, full length human CCL2 (MCP-1) protein (amino acids 1–99) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.2 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_779578 |
Product Specific Information
Neutralization: Tested on the ability to inhibit monocyte chemotaxis toward 1 nM recombinant human MCP-1 in blindwell chambers. The antibody effectively blocked MCP-1 activity at 0.5 µg/mL and inhibited the function of native MCP-1 at similar concentrations.
Target Information
This gene encodes a cytokine belonging to the CC chemokine family, clustered on the q-arm of chromosome 17. These cytokines are secreted proteins involved in immunoregulatory and inflammatory processes. MCP-1 (CCL2) exhibits chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It is implicated in diseases with monocytic infiltrates such as psoriasis, rheumatoid arthritis, and atherosclerosis. MCP-1 binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.