Thermo Fisher Scientific RPS17 Polyclonal Antibody
Thermo Fisher Scientific의 RPS17 폴리클로날 항체는 인간 RPS17 단백질을 인식하며 WB, IHC(P), ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 완충액에 보관됩니다. 단백질 합성 연구 및 Diamond-Blackfan 빈혈 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RPS17. Recombinant protein control fragment (Product #RP-100843) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646780 |
Product Specific Information
Immunogen sequence:
RGISIKLQEE ERERRDNYVP EVSALDQEII EVDPDTKEML KL
Highest antigen sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
Ribosomes are organelles responsible for catalyzing protein synthesis and consist of a small (40S) and large (60S) subunit containing over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families with processed pseudogenes and one functional intron-containing gene.
Ribosomal Protein S17 (RPS17, RPS17L1, RPS17L2) is a 135-amino-acid component of the 40S subunit, localized in the cytoplasm and expressed ubiquitously. It belongs to the S17e family and functions in protein synthesis. Mutations in the RPS17 gene are associated with Diamond-Blackfan anemia (DBA), a congenital disorder characterized by defective differentiation of pro-erythroblasts. RPS17 also exists as multiple processed pseudogenes scattered throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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