Thermo Fisher Scientific UBE4a Polyclonal Antibody
Human UBE4a 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액에 보관. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
- Publications: -
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBE4a. Recombinant protein control fragment (Product #RP-102399) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649190 |
Product Specific Information
Immunogen sequence:
LKQQSDELPA SPDDSDNSVS ESLDEFDYSV AEISRSFRSQ QEICEQLNIN HMIQRIFLIT LDNSDPSLKS GNGIPSRCVY LEEMAVELED QDWLDMSNVE QALFARLLLQ DPGNHLINMT SSTTLNLSAD RDAGER
- Highest antigen sequence identity to orthologs:
- Mouse: 96%
- Rat: 94%
Target Information
Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor to bind to ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins.
Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4.
In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eukaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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