Thermo Fisher Scientific Phospho-CDK2 (Thr160) Polyclonal Antibody
CDK2 단백질의 Thr160 인산화 형태를 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 사용 가능. 합성 인산화 펩타이드로부터 제작. 연구용으로 세포주기 관련 단백질 분석에 적합.
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- PA112684
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to phosphorylated human CDK2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1086275 |
Product Specific Information
A suggested positive control for this product is recombinant CDK2.
Target Information
CDK2/cyclinO is a member of the cyclin-dependent protein kinase family complexed to CyclinO. CyclinO is a specific protein isoform of the UNG gene, localized exclusively in the nucleus, and exhibits uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during the G1 phase and are turned over during the cell cycle. Cyclin A–CDK2 levels peak at the G1/S transition, and both CDK2 and Cyclin A associate with DNA in the initiation complex during replication. The Rb protein acts as a substrate for CDK2–Cyclin E and/or CDK2–Cyclin A in vivo. CDK2 is activated and localized to the nucleus during late G1, S, and G2 phases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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