Thermo Fisher Scientific EDG4 Polyclonal Antibody
EDG4 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. Human 시료에 반응하며, PBS buffer에 0.08% sodium azide를 포함한 액상 형태입니다. RH7777 세포를 양성 대조군으로 추천합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA112694
- 판매단위
- pk
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human EDG4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2281181 |
Product Specific Information
A suggested positive control for this product is RH7777 cells transfected with EDG4 protein.
Target Information
Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes.
In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion.
Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis.
It has also been observed in various cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid.
ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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