Thermo Fisher Scientific IL-12/IL-23 p40 Recombinant Rabbit Monoclonal Antibody (101)
마우스 IL-12/IL-23 p40 단백질을 인식하는 재조합 토끼 단클론 항체입니다. ELISA에 적합하며 높은 특이성과 재현성을 제공합니다. 보존제가 포함되지 않아 실험 조건에 맞게 나트륨 아지드 첨가 권장. 단기 4℃, 장기 -20℃ 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IL-12/IL-23 p40 Recombinant Rabbit Monoclonal Antibody (101)
Applications
Tested Application
- ELISA (ELISA)
Recommended Dilution
- 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 101 |
| Immunogen | Recombinant Mouse IL-23 (IL23A & IL12B Heterodimer) Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786422 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal production clones.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the large rabbit immune repertoire
This antibody specifically recognizes Mouse IL-23 (IL23A & IL12B Heterodimer).
Target Information
IL-12 is an interleukin produced by dendritic cells, neutrophils, macrophages, and human lymphoblastoid cells upon antigenic stimulation.
It is a heterodimeric cytokine composed of IL-12A (p35) and IL-12B (p40) subunits.
IL-23 shares the IL-12B subunit with IL-12 and includes an IL-23A (IL-23p19) subunit.
Functionally, IL-12 increases vascular endothelial adhesion molecule-1 expression, directs leukocyte migration toward tumors, and facilitates ischemic-hemorrhagic necrosis of tumor tissue.
In contrast, IL-23 is critical for stimulating memory T-cells and the induction, expansion, and maintenance of Th17 cells, which regulate neutrophil chemokines and pro-inflammatory cytokines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.