Thermo Fisher Scientific HIP1 Polyclonal Antibody
HIP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간 시료 반응성. N-terminal 합성 펩타이드 면역원 사용, 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human HIP1 (aa 338–387) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610530 |
Product Specific Information
Peptide sequence:
SQQNLFDNKF DDIFGSSFSS DPFNFNSQNG VNKDEKDHLI ERLYREISGL
Target Information
Huntingtin disease, a neurodegenerative disorder, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a proapoptotic, cargo-specific adaptor protein possibly involved in the pathogenesis of Huntingtin disease. HIP-1 also plays a role in clathrin coat recruitment to lipid membranes and may contribute to tumorigenesis by supporting survival of precancerous and cancerous cells. Since HIP-1 expression correlates with prostate and colon cancer metastasis, it can serve as a prognostic marker for these cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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