Thermo Fisher Scientific WDR21A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt.

Target Information

The nuclear protein p100 is a proliferation-associated protein expressed in cell cycle phases S, G2, and M. It is exclusively expressed in proliferating cells from the G1/S transition until cytokinesis. During mitosis, it associates with the spindle pole and mitotic spindle; during S and G2 phases, it is diffusely distributed throughout the nucleus.
The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis shows strong expression in lung carcinoma cell lines but not in normal lung tissues. Expression is also found in adult placenta, skeletal muscle, thymus, testis, small intestine, and in fetal brain, liver, and kidney. P100 expression correlates with cancer prognosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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