Thermo Fisher Scientific TMC1 Polyclonal Antibody
TMC1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC에 사용 가능. 인간과 생쥐에 반응하며, 합성 펩타이드 항원을 기반으로 제작됨. 동결건조 형태로 제공되며 연구용으로만 사용 가능.
- 카탈로그번호
- OST00173W-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TMC1 Polyclonal Antibody
Thermo Fisher Scientific TMC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:1,000–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from human TMC1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term; at -20°C for long term. Avoid freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous with the corresponding sequence in mouse.
- Specificity: TMC1.
Target Information
SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat.
The SLP-76 locus has been localized to human chromosome 5q33 and partially characterized in mice.
Human and murine cDNAs encode 533 amino acid proteins that are 72% identical and composed of three modular domains:
- NH2-terminus contains an acidic region with a PEST domain and tyrosine residues phosphorylated after TCR ligation.
- Central proline-rich domain.
- COOH-terminal SH2 domain.
SLP-76 interacts with various proteins constitutively and inducibly following receptor ligation, acting as an adaptor or scaffold protein.
Studies using SLP-76 deficient T cell lines or mice show its role in promoting T cell development, activation, mast cell, and platelet function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.