
Thermo Fisher Scientific EPCAM Monoclonal Antibody (OTI2G9), TrueMAB
EpCAM 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot, IHC, Flow cytometry 등에 적합합니다. 고순도 Affinity chromatography로 정제된 액상 형태이며, PBS/BSA/glycerol 버퍼에 보관됩니다. 인간 EpCAM 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G9 |
| Immunogen | Full length human recombinant protein of human EPCAM produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in epithelial tissues, with a molecular weight of approximately 40 kDa. It functions as a calcium-independent cell adhesion molecule and influences cell cycle, proliferation, and metabolism through induction of proto-oncogene c-myc and cyclin A/E. Ep-CAM-mediated adhesions negatively regulate cadherin-mediated adhesions, affecting epithelial differentiation and growth. Overexpression is associated with enhanced epithelial proliferation and is a marker for epithelial lineage tumors, distinguishing adenocarcinomas from pleural mesotheliomas.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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