Thermo Fisher Scientific SMARCB1 Monoclonal Antibody (3E3)
SMARCB1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot 및 ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. PBS 용액 내 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E3 |
| Immunogen | SMARCB1 (NP_003064, 81–180 a.a.) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
YTTLATSVTL LKASEVEEIL DGNDEKYKAV SISTEPPTYL REQKAKRNSQ WVPTLPNSSH HLDAVPCSTT INRNRMGRDK KRTFPLCFDD HDPAVIHENATarget Information
The SWI-SNF complex is involved in activation of transcription via ATP-dependent nucleosome remodeling.
Brm (SNF2α) and Brg-1 (SNF2β) are ATPase subunits of the mammalian SWI-SNF complex.
Core components include Brm, Brg-1, Ini1 (SNF5), BAF155 (SRG3), and BAF170.
Addition of Ini1, BAF155, and BAF170 to Brg-1 increases remodeling activity.
Other subunits play regulatory roles.
hSNF2L and hSNF2H are homologs of Drosophila ISWI, found in other chromatin remodeling complexes such as NURF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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