Thermo Fisher Scientific GPNMB Polyclonal Antibody
GPNMB 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunocytochemistry에 적합하며, Affinity chromatography로 정제되었습니다. PBS와 50% glycerol buffer에 보관되며 -20°C에서 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GPNMB (Accession Q14956), corresponding to amino acid residues P327–F377 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899952 |
Product Specific Information
This antibody detects endogenous levels of total GPNMB.
Target Information
The protein encoded by this gene is a type I transmembrane glycoprotein homologous to the pMEL17 precursor, a melanocyte-specific protein. GPNMB is expressed in lowly metastatic human melanoma cell lines and xenografts but not in highly metastatic cell lines. It may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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