Thermo Fisher Scientific ATOH1 Polyclonal Antibody
ATOH1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. 면역세포염색(ICC/IF)에 적합하며, 고순도의 Affinity chromatography로 정제되었습니다. 장기 보관 시 -20°C에서 안정적으로 보관 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 206–341). Recombinant protein control fragment: Product # RP-110172 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091880 |
Product Specific Information
Immunogen sequence:
IYINALSELL QTPSGGEQPP PPPASCKSDH HHLRTAASYE GGAGNATAAG AQQASGGSQR PTPPGSCRTR FSAPASAGGY SVQLDALHFS TFEDSALTAM MAQKNLSPSL PGSILQPVQE ENSKTSPRSH RSDGEF
Antigen sequence identity:
- Mouse: 84%
- Rat: 83%
Target Information
The Drosophila atonal gene encodes a protein with basic helix-loop-helix (bHLH) domains that are crucial for nervous system development. The mammalian homolog, Atonal homolog 1 (MATH-1, also known as Atoh1, Ath1, or HATH-1), is a 351 amino acid HLH transcription factor structurally similar to the Drosophila proneural gene product.
In mice, MATH-1 expression begins around embryonic day 9.5, localizing to cranial ganglia and the dorsal CNS. By day 18, expression becomes restricted to the external granular layer of the cerebellum and is undetectable in adults. MATH-1 is believed to regulate the differentiation of neural cell subsets by activating E-box-dependent transcription.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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