Thermo Fisher Scientific SF3B2 Monoclonal Antibody (5D2)
SF3B2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 인간, 마우스, 랫트 반응성. WB, IHC, ICC/IF, ELISA에 사용 가능. 친화 크로마토그래피로 정제된 액상 형태이며, 보존제가 포함되지 않음. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 6 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D2 |
| Immunogen | SF3B2 (NP_006833, 592–645 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
YEGKEFETRL KEKKPGDLSD ELRISLGMPV GPNAHKVPPP WLIAMQRYGP PPSY
Target Information
Subunit of the splicing factor SF3B required for A complex assembly formed by stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA.
Sequence-independent binding of SF3A/SF3B complex upstream of the branch site is essential; it may anchor U2 snRNP to the pre-mRNA.
May also be involved in the assembly of the E complex.
Belongs to the minor U12-dependent spliceosome, which is involved in splicing of a rare class of nuclear pre-mRNA introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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