Thermo Fisher Scientific SF3B2 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SF3B2 (AAH07610.1, 1 a.a. approximately 636 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SF3B2,uniProtId:Q13435-1,ncbiNodeId:9606,antigenRange:1-895,antigenLength:895,antigenImageFileName:H00010992-B01P_SF3B2_Q13435-1_House_mouse.svg,antigenImageFileNamePDP:H00010992-B01P_SF3B2_Q13435-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MDDPSVGPKI PQALEKILQL KESRQEEMNS QQEEEEMETD ARSSLGQSAS ETEEDTVSVS KKEKNRKRRN RKKKKKPQRV RGVSSESSGD REKDSTRSRG SDSPAADVEI EYVTEEPEIY EPNFIFFKRI FEAFKLTDDV KKEKEKEPEK LDKLENSAAP KKKGFEEEHK DSDDDSSDDE QEKKPEAPKL SKKKLRRMNR FTVAELKQLV ARPDVVEMHD VTAQDPKLLV HLKATRNSVP VPRHWCFKRK YLQGKRGIEK PPFELPDFIK RTGIQEMREA LQEKEEQKTM KSKMREKVRP KMGKIDIDYQ KLHDAFFKWQ TKPKLTIHGD LYYEGKEFET RLKEKKPGDL SDELRISLGM PVGPNAHKVP PPWLIAMQRY GPPPSYPNLK IPGLNSPIPE SCSFGYHAGG WGKPPVDETG KPLYGDVFGT NAAEFQTKTE EEEIDRTPWG ELEPSDEESS EEEEEEESDE DKPDETGFIT PADSGLITPG GFSSVPAGME TPELIELRKK KIEEAMDGSE TPQLFTVLPE KRTATVGGAM MGSTHIYDMS TVMSRKGPAP ELQGVEVALA PEELELDPMA MTQKYEEHVR EQQAQVEKED FSDMVAEHAA KQKQKKRKAQ PQDSRGGSKK YKEFKF

Target Information

Subunit of the splicing factor SF3B required for A complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the E complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.