Thermo Fisher Scientific SF3B2 Polyclonal Antibody, MaxPab
SF3B2 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot과 면역세포화학(ICC/IF)에 적합하며, 인간 시료에 반응합니다. 액상 형태로 제공되며, PBS buffer에 보존되어 -20°C에서 보관합니다.
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Thermo Fisher Scientific SF3B2 Polyclonal Antibody, MaxPab
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SF3B2 (AAH07610.1, 1 a.a. ~ 636 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDDPSVGPKI PQALEKILQL KESRQEEMNS QQEEEEMETD ARSSLGQSAS ETEEDTVSVS KKEKNRKRRN RKKKKKPQRV RGVSSESSGD REKDSTRSRG SDSPAADVEI EYVTEEPEIY EPNFIFFKRI FEAFKLTDDV KKEKEKEPEK LDKLENSAAP KKKGFEEEHK DSDDDSSDDE QEKKPEAPKL SKKKLRRMNR FTVAELKQLV ARPDVVEMHD VTAQDPKLLV HLKATRNSVP VPRHWCFKRK YLQGKRGIEK PPFELPDFIK RTGIQEMREA LQEKEEQKTM KSKMREKVRP KMGKIDIDYQ KLHDAFFKWQ TKPKLTIHGD LYYEGKEFET RLKEKKPGDL SDELRISLGM PVGPNAHKVP PPWLIAMQRY GPPPSYPNLK IPGLNSPIPE SCSFGYHAGG WGKPPVDETG KPLYGDVFGT NAAEFQTKTE EEEIDRTPWG ELEPSDEESS EEEEEEESDE DKPDETGFIT PADSGLITPG GFSSVPAGME TPELIELRKK KIEEAMDGSE TPQLFTVLPE KRTATVGGAM MGSTHIYDMS TVMSRKGPAP ELQGVEVALA PEELELDPMA MTQKYEEHVR EQQAQVEKED FSDMVAEHAA KQKQKKRKAQ PQDSRGGSKK YKEFKF
Target Information
Subunit of the splicing factor SF3B required for A complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence-independent binding of SF3A/SF3B complex upstream of the branch site is essential; it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the E complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of a rare class of nuclear pre-mRNA intron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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