Thermo Fisher Scientific Noelin Polyclonal Antibody, FITC
FITC로 표지된 Noelin-1 단백질 특이적 Rabbit Polyclonal 항체. Western blot, ELISA, IP 등 다양한 응용에 적합. 498/517 nm 형광 특성. Affinity chromatography로 정제되어 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | N-epitope synthetic peptide within amino acid region 1–60 on Noelin-1 protein |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | –20 °C, store in dark |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Olfactomedin family comprises a diverse group of secreted glycoproteins, including OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin, and myocilin. These proteins are implicated in the development of the nervous system.
Specifically, OLFM1 and OLFM2 expression occurs in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8–10, and later in brain tissue and in the zone of polarizing activity in the limb.
Overexpression of OLFM1 causes excess neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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