Thermo Fisher Scientific Noelin Polyclonal Antibody, Biotin
Mouse Noelin-1 단백질을 인식하는 Biotin 결합 Rabbit Polyclonal Antibody로, WB, ELISA, IP 등 다양한 면역실험에 사용 가능. 고순도 Affinity Chromatography 정제, 안정적 액상 형태로 -20°C 보관. 신경계 발달 관련 연구에 적합.
- 카탈로그번호
- NOE-100-BIOTIN
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | N-epitope synthetic peptide within amino acid region 1–60 on Noelin-1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Olfactomedin family comprises a diverse group of secreted glycoproteins, including OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin, and mycocilin. These proteins are involved in nervous system development. OLFM1 and OLFM2 expression is observed in the neural plate, neural crest, and cranial ganglia in mouse embryos (E8–10), as well as in brain tissue and limb zone of polarizing activity. Overexpression of OLFM1 leads to excess neural crest emigration and prolonged neural crest production. OLFM2 regulates anterior nervous system development, and an Arg144Gln mutation in OLFM2 may be associated with open-angle glaucoma (OAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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