Thermo Fisher Scientific Phospho-PDE3B (Ser303) Polyclonal Antibody
Phospho-PDE3B (Ser303) 폴리클로날 항체로, Western blot, ELISA, IP에 사용 가능. Rabbit 유래 IgG 항체이며 다양한 종(인간, 마우스, 랫, 닭 등)에 반응. 합성 펩타이드 면역원으로 제작되어 PDE3B 변이체에 특이적. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 260–310 on rat PDE3B protein. Selective for PDE3B variant. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotide phosphodiesterase with dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6, assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and involved in angiogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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