Thermo Fisher Scientific EBP1 Polyclonal Antibody
EBP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응. WB, IHC(P), ELISA에 적합하며, 세포 성장 조절 및 리보솜 조립 관련 연구에 유용. Affinity Chromatography로 정제된 고품질 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–394 of human EBP1/PA2G4 (NP_0061822) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.24 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805671 |
Product Specific Information
Immunogen sequence:
MSGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL KEGDLVKIDL GVHVDGFIAN VAHTFVVDVA QGTQVTGRKA DVIKAAHLCA EAALRLVKPG NQNTQVTEAW NKVAHSFNCT PIEGMLSHQL KQHVIDGEKT IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA GQRTTIYKRD PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ DAELKALLQS SASRKTQKKK KKKASKTAEN ATSGETLEEN EAGD
Positive Samples: HT-29, 22Rv1, K-562, BxPC-3, Mouse spleen
Cellular Location: Cytoplasm, Nucleus, Nucleolus
Target Information
This gene encodes an RNA-binding protein involved in growth regulation. It is present in pre-ribosomal ribonucleoprotein complexes and may play a role in ribosome assembly and rRNA processing.
EBP1 interacts with the cytoplasmic domain of the ErbB3 receptor, contributing to growth regulatory signaling.
It functions as a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through interactions with histone deacetylases.
EBP1 is implicated in growth inhibition and differentiation induction of human cancer cells.
Six pseudogenes are located on chromosomes 3, 6, 9, 18, 20, and X.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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