Thermo Fisher Scientific TrkC Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human TrKC (NP_0010071571) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TrkC,uniProtId:Q16288-1,ncbiNodeId:9606,antigenRange:40-300,antigenLength:839,antigenImageFileName:PA5-89587_TrkC_Q16288-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89587_TrkC_Q16288-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.92 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805670

Product Specific Information

Immunogen sequence: KTEINCRRPD DGNLFPLLEG QDSGNSNGNA SINITDISRN ITSIHIENWR SLHTLNAVDM ELYTGLQKLT IKNSGLRSIQ PRAFAKNPHL RYINLSSNRL TTLSWQLFQT LSLRELQLEQ NFFNCSCDIR WMQLWQEQGE AKLNSQNLYC INADGSQLPL FRMNISQCDL PEISVSHVNL TVREGDNAVI TCNGSGSPLP DVDWIVTGLQ SINTHQTNLN WTNVHAINLT LVNVTSEDNG FTLTCIAENV VGMSNASVAL T; Positive Samples: A549, HepG2, Mouse liver; Cellular Location: Membrane, Single-pass type I membrane protein

Target Information

NTRK3 (TRKC) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.