Thermo Fisher Scientific OLIG2 Monoclonal Antibody (3D7)
OLIG2 단백질을 인식하는 Mouse Monoclonal Antibody(3D7)로, WB, ICC/IF, ELISA, IP에 사용 가능. 인간 시료 반응성 확인됨. PBS(pH 7.4) 용액 형태로 제공되며, 보존제 무첨가. -20°C에서 보관, 동결/해동 반복 피할 것.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3D7 |
| Immunogen | OLIG2 (NP_005797, 2 a.a. – approximately 78 a.a.) full length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
DSDASLVSSR PSSPEPDDLF LPARSKGSSG SAFTGGTVSS STPSDCPPEL SAELRGAMGS AGAHPGDKLG GSGFKSS
Target Information
This gene encodes a basic helix-loop-helix transcription factor expressed in oligodendroglial tumors of the brain. The protein regulates ventral neuroectodermal progenitor cell fate and is involved in chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia.
Its chromosomal region on chromosome 21 may contribute to learning deficits associated with Down syndrome.
Tissue specificity:
- Expressed in brain, particularly in oligodendrocytes
- Strongly expressed in oligodendrogliomas
- Weak to moderate expression in astrocytomas
- Variable expression in glioblastomas
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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