Thermo Fisher Scientific GDF11 Monoclonal Antibody (3G6)
GDF11 단백질을 인식하는 Mouse IgG2b 단클론 항체로, 인간 시료에 반응합니다. IHC(P) 및 ELISA에 적용 가능하며, PBS(pH 7.4) 용액 형태로 제공됩니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G6 |
| Immunogen | GDF11 (NP_005802, approximately 310–407 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
ESRCCRYPLT VDFEAFGWDW IIAPKRYKAN YCSGQCEYMF MQKYPHTHLV QQANPRGSAG PCCTPTKMSP INMLYFNDKQ QIIYGKIPGM VVDRCGCS
Target Information
GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily.
This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues.
Members of this family regulate cell growth and differentiation in both embryonic and adult tissues.
Studies in mice and Xenopus suggest that GDF11 is involved in mesodermal formation and neurogenesis during embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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