Thermo Fisher Scientific GDF11 Monoclonal Antibody (3G6)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

3G6

Immunogen

GDF11 (NP_005802, 310 a.a. approximately 407 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GDF11,uniProtId:O95390-1,ncbiNodeId:9606,antigenRange:310-407,antigenLength:407,antigenImageFileName:H00010220-M01_GDF11_O95390-1_House_mouse.svg,antigenImageFileNamePDP:H00010220-M01_GDF11_O95390-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: ESRCCRYPLT VDFEAFGWDW IIAPKRYKAN YCSGQCEYMF MQKYPHTHLV QQANPRGSAG PCCTPTKMSP INMLYFNDKQ QIIYGKIPGM VVDRCGCS

Target Information

GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.