Thermo Fisher Scientific SNX6 Polyclonal Antibody
SNX6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A로 정제된 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SNX6, amino acids 211–310 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SNX6 interacts with members of the transforming growth factor-beta (TGF-β) family of receptor serine-threonine kinases. These receptors include type II receptors that bind ligand and type I receptors that transduce the signal. SNX6 interacts strongly with ActRIIB and moderately with wild-type and kinase-defective mutants of TβRII. Among type I receptors, SNX6 interacts only with inactivated TβRI. SNXs 1–4 also interact with the TGF-β receptor family, showing different receptor preferences. SNX6 exhibits similar behavior to other SNX proteins in receptor tyrosine kinase interactions and forms heteromeric complexes with SNX1, SNX2, SNX4, and SNX6, suggesting oligomeric complex formation in vivo. These findings support the association of the SNX family with receptor serine-threonine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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